Applications Why 370 uva? Wavelength Technical SpecificationsRelated Products

Wavelength

The wavelength 370 nm hat some decisive advantages for dermatology. UV-damaged DNA is a basic molecular target structure of UV-mediated immunosuppression. These effects can be used selectively for the therapy of diverse types of dermatosis in which the cellular immunity has been disrupted. The external stimulation can induce a normalization of the immune answer of the skin. UVA (315 - 400 nm) has a deeper penetration into the skin, as compared to UVB (280 - 315 nm). UVA can reach into the dermis.

The immune suppressive effects of UV radiation on the immune system have important biological and clinical relevance, as they contribute to photocarcinogenesis:

• They inhibit the presentation of antigens.
• They stimulate the release of immune-suppressive zytokins.
• They induce regulatory t-lymphocytes.

UVA radiation has a lower risk of side effects than UVB: The absorption of UVB by DNA is high, which can lead to damage. This in turn increases the risk of cancerogenesis.

Legal Advice
_{Product specifications and approved applications may vary for products sold in the United States of America.
> more}